Insights in Chest Diseases

Body Composition, Inflammation, Physical Exercises and Food Intake in Cystic Fibrosis: Cross-Sectional Study

Introduction: The body composition detects earlier impairment of the nutritional status and it may be altered by chronic inflammation, physical activity and energetic imbalance.
Methods: It is a cross-sectional study with 46 patients from 8 to 18 years old with CF aged 11.9 ± 2.83 years. We evaluated the arm muscle area, ratio of the subscapular and triceps skinfolds, body fat percentage, 24 h dietary recall, physical activity, C-reactive protein, and cytokines. It was made descriptive statistics, univariate and multiple linear regressions.
Findings: Among the patients studied, 52.2% were undernourished, 26.1% owned low body fat percentage and 55.6% increase in abdominal fat. The physical inactivity, inadequate intake, increased age and interleukin 8 contribute to the increase of body fat (p<0.05). The prevalence of malnutrition was 1.9 times higher in those with high C-reactive protein. The prevalence of malnutrition was 1.9 times higher in those with high C-reactive protein. There was a positive association of Interleucine-8 with body fat percentage and ratio of skinfolds.
Conclusions: The C-reactive protein may be considered a prognostic indicator of malnutrition. The total energetic intake and level of physical activity are factors of preservation of lean body mass. The positive association of interleukins 8 with the percentage of body fat seems to be more associated with obesity.

Author(s):

Chaves CRMM, Cunha ALP, Aquino CVMNG, Carioca AC and Fonseca VM

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